ASCO and the Oncology Nursing Society (ONS) have been working jointly over the past year to augment the existing ASCO/ONS Standards for Safe Chemotherapy Administration with additional standards focused on oral chemotherapy administration. This work recognizes the expansion of the use of oral agents in the oncology office and the special safety concerns related to these agents. The development methodology for the oral chemotherapy safety standards included a multi-stakeholder consensus meeting, an open public comment period, and review by the ASCO and ONS Boards of Directors. The standards were approved by ASCO and ONS in November 2012 and will be published in 2013. For more information, visit asco.org/safety.