Exclusive Coverage articles provide quick insight and additional author perspectives on select studies recently published in Journal of Clinical Oncology and Journal of Oncology Practice.
For Some Patients, Symptoms of Oxaliplatin-Induced Neuropathy Do Not Abate Between Cycles: Findings from a Phase III Trial
Aug 31, 2015 4:04 PM
A new study in the Journal of Clinical Oncology (JCO) revealed several new findings about the four main symptoms of oxaliplatin-induced acute neuropathy and how these symptoms play out over time among oncology patients in a clinical setting. Neuropathy manifests as pain, numbness, tingling, or muscle weakness in the feet, hands,...
Adding Olaparib to Paclitaxel is Associated with Greater Overall Survival in Patients with Advanced Gastric Cancer
Aug 24, 2015 4:11 PM
Lab studies have shown that gastric cancer cell lines with low levels of ataxia telangiectasia mutated (ATM)—which plays a key role in activating the repair response to DNA damage—are particularly sensitive to olaparib, a poly (ADP-ribose) polymerase (PARP) inhibitor. PARP inhibitors target tumors with deficiencies in the repair of double-strand...
Apply Today for Conquer Cancer Foundation Young Investigator Award in Fibrolamellar Hepatocellular Carcinoma
Aug 21, 2015 2:40 PM
When Tucker Davis was diagnosed with fibrolamellar hepatocellular carcinoma (FL-HCC) in 2008, there was very little information available about this very rare cancer and, as Tucker would soon discover, even fewer treatment options.
“Does Smoking Affect My Prognosis?” Older and Younger Survivors’ Perception of Behavioral Modifications
Aug 10, 2015 4:23 PM
A new study in the Journal of Oncology Practice (JOP), “Lifestyle Behaviors in Elderly Cancer Survivors: A Comparison with Middle-Age Cancer Survivors,” found that older patients—defined as 65 and older—differ significantly from younger patients in terms of how they perceive behavioral modifications in smoking and alcohol...
Study Identifies Factors Associated with Increased Risk for Melanoma Among Survivors of Non-Hodgkin Lymphoma
Aug 04, 2015 9:40 AM
A study in JCO has identified two factors associated with the increased risk of melanoma in survivors of NHL who are 65 years and older—treatment with fludarabine and autoimmune conditions.
Jul 20, 2015 4:01 PM
A study out of the Smilow Cancer Hospital (SCH) in New Haven, Connecticut, assessed the outcomes of an intervention designed to address barriers clinicians face in documenting patients’ emotional distress. The study, “Incorporating Patient-Reported Outcomes to Improve Emotional Distress Screening and Assessment in an Ambulatory Oncology Clinic,”...
Alzheimer’s Drug Associated with Significant Cognitive Improvements Among Recipients of Brain Irradiation
Jul 13, 2015 3:58 PM
Brain irradiation for primary and metastatic brain tumors has long been known to cause neurotoxic effects, including cognitive impairments. Among the 200,000 people yearly who undergo whole-brain irradiation (WBI) and the 15,000 who undergo partial-brain irradiation (PBI)...
Jul 06, 2015 4:11 PM
Why do some women with breast cancer discontinue adjuvant hormone therapy, such as tamoxifen and aromatase inhibitors? That’s the question at the heart of a study carried out by researchers at the Karolinska Institute in Stockholm, Sweden and the University of Maryland, Baltimore...
Jun 29, 2015 4:23 PM
Numerous studies have shown that patients who receive early palliative experience greater physical health and quality of life—and that these benefits extend to patients’ families as well. Studies have also shown that palliative care, which includes the management of symptoms such as pain, nausea, and anxiety; psychosocial counseling; and...
Jun 22, 2015 4:03 PM
For years now, researchers have been turning the neat, legible, type-written notes within electronic health records (EHRs) to uncover a treasure-trove of patient data...