Exclusive Journals Coverage articles provide quick insight and additional author perspectives on select studies recently published in Journal of Clinical Oncology and Journal of Oncology Practice.
Children Treated for ALL Experience Varying Levels of Cognitive Deficits—and Genetic Susceptibility to Oxidative Stress Might be a Factor
May 18, 2015
Numerous studies have shown that children treated for acute lymphoblastic leukemia (ALL) experience increased rates of cognitive deficits in terms of attention span, working memory, and processing complex information.
Benefits of Intraperitoneal Chemotherapy Extend Beyond 10 Years; Survival Increases with Number of Cycles
May 11, 2015
Several clinical trials have shown that for women with ovarian cancer, IP chemotherapy–which allows the drugs to be delivered directly into the peritoneum at a 20- to 1000-fold greater concentration than IV chemotherapy—confers survival advantages.
May 04, 2015
During the past two decades, there has been an increase in the number of long-term survivors of autologous and allogeneic hematopoietic stem-cell transplantations (HSCT).
No Difference in Survival Between Cisplatin and Carboplatin for Metastatic or Recurrent Cervical Cancer
Apr 27, 2015
For women with metastatic or recurrent cervical cancer, paclitaxel plus carboplatin confers the same survival advantage as paclitaxel plus cisplatin, currently the standard of care (overall survival [OS] was 17.5 months in the carboplatin group versus 18.3 months in the cisplatin group)...
Apr 13, 2015
The study found that among the 35% of patients who expressed a strong desire for genetic testing, 196 (43.4%) did not have a relevant discussion...
Apr 06, 2015
A study in the Journal of Clinical Oncology (JCO) set out to answer two questions: What are the rates of adherence to these new distress-screening and referral requirements at two tertiary cancer care centers and, do clinicians find the screening useful?
Mar 23, 2015
“Physicians who are part of a larger, more integrated care delivery system might be better able to plan a response to a drug shortage. Another possibility is that larger organizations have more purchasing power or ability to engage in the market.”
JCO Exclusive: Testosterone Matters: Keeping Levels Low Among Men with Prostate Cancer Improves Survival
Mar 16, 2015
Among patients with prostate cancer being treated with continuous (non-intermittent) androgen deprivation therapy, those whose testosterone dipped to a nadir of less than 20 nanograms per deciliter within the first year of treatment experienced improved survival and . . .
Mar 09, 2015
For children and adolescents being treated for acute lymphoblastic leukemia, those who receive a stem-cell transplant from an unrelated donor have the same overall survival as those who receive the transplant from a sibling.
JCO Exclusive: In Sorafenib-Treated HCC, Prophylactic Use of Urea-Based Cream Improves Hand-Foot Skin Reaction
Mar 02, 2015
"The study found that over a 14-week period, incidence of HFSR—of any grade—was lower among patients who started using the urea-based cream at the start of treatment, compared to patients who received best supportive care alone."