Every year, the Conquer Cancer Foundation funds research grants that provide critical start-up funding for young physician-scientists, with the goal of enabling them to develop a successful career in cancer research so that they can bring new treatments into the clinic and improve the lives of patients with cancer. Clearly, the programs are working: three studies featured in the recently released Clinical Cancer Advances 2012: Annual Report on Progress Against Cancer From the American Society of Clinical Oncology, which identifies the top advances of the year in clinical cancer research, were funded in part by Conquer Cancer Foundation of ASCO Career Development Awards.